Which mouth rinse formulation binds to oral tissues but may cause a burning sensation and epithelial desquamation?

The mouth rinse formulation that binds to oral tissues and may cause a burning sensation and epithelial desquamation is the quaternary ammonium compound. These compounds are known for their antimicrobial properties and are commonly used in mouth rinses to help reduce plaque and gingivitis. However, their tendency to adhere to mucosal tissues can lead to localized irritation, resulting in a burning sensation, and in some cases, can contribute to the shedding of epithelial cells, known as epithelial desquamation.

This characteristic makes quaternary ammonium compounds effective in terms of their binding qualities, but the potential side effects should be considered when recommending or using these products. Other formulations like hydrogen peroxide primarily act as a bleaching agent with minimal tissue binding properties. Sodium fluoride and stannous fluoride are fluoride compounds focused on caries prevention and remineralization of enamel, and they do not typically cause the side effects associated with quaternary ammonium compounds. Thus, the distinct properties and side effects of quaternary ammonium compounds highlight why this answer is appropriate.